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Spectroscopic Studies of the Iron and Manganese Reconstituted Tyrosyl Radical in Bacillus Cereus Ribonucleotide Reductase R2 Protein

Ribonucleotide reductase (RNR) catalyzes the rate limiting step in DNA synthesis where ribonucleotides are reduced to the corresponding deoxyribonucleotides. Class Ib RNRs consist of two homodimeric subunits: R1E, which houses the active site; and R2F, which contains a metallo cofactor and a tyrosyl...

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Detalles Bibliográficos
Autores principales: Tomter, Ane B., Zoppellaro, Giorgio, Bell, Caleb B., Barra, Anne-Laure, Andersen, Niels H., Solomon, Edward I., Andersson, K. Kristoffer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303829/
https://www.ncbi.nlm.nih.gov/pubmed/22432022
http://dx.doi.org/10.1371/journal.pone.0033436