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Hypoxia Inducible Factor 1-Alpha (HIF-1 Alpha) Is Induced during Reperfusion after Renal Ischemia and Is Critical for Proximal Tubule Cell Survival

Acute tubular necrosis (ATN) caused by ischemia/reperfusion (I/R) during renal transplantation delays allograft function. Identification of factors that mediate protection and/or epithelium recovery could help to improve graft outcome. We studied the expression, regulation and role of hypoxia induci...

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Detalles Bibliográficos
Autores principales: Conde, Elisa, Alegre, Laura, Blanco-Sánchez, Ignacio, Sáenz-Morales, David, Aguado-Fraile, Elia, Ponte, Belén, Ramos, Edurne, Sáiz, Ana, Jiménez, Carlos, Ordoñez, Angel, López-Cabrera, Manuel, del Peso, Luis, de Landázuri, Manuel O., Liaño, Fernando, Selgas, Rafael, Sanchez-Tomero, Jose Antonio, García-Bermejo, María Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303832/
https://www.ncbi.nlm.nih.gov/pubmed/22432008
http://dx.doi.org/10.1371/journal.pone.0033258