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Differentiation Potential of CD14(+) Monocytes into Myofibroblasts in Patients with Systemic Sclerosis

BACKGROUND: Circulating monocytes are a highly plastic and functionally heterogeneic cell type with an activated phenotype in patients with systemic sclerosis (SSc). CD14(+) monocytes have the potential to differentiate into extra-cellular matrix (ECM) producing cells, possibly participating in fibr...

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Detalles Bibliográficos
Autores principales: Binai, Nadine, O'Reilly, Steven, Griffiths, Bridget, van Laar, Jacob M., Hügle, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303833/
https://www.ncbi.nlm.nih.gov/pubmed/22432031
http://dx.doi.org/10.1371/journal.pone.0033508