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Comparison of the Gene Expression Profiles from Normal and Fgfrl1 Deficient Mouse Kidneys Reveals Downstream Targets of Fgfrl1 Signaling

Fgfrl1 (fibroblast growth factor receptor-like 1) is a transmembrane receptor that is essential for the development of the metanephric kidney. It is expressed in all nascent nephrogenic structures and in the ureteric bud. Fgfrl1 null mice fail to develop the metanephric kidneys. Mutant kidney rudime...

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Detalles Bibliográficos
Autores principales: Gerber, Simon D., Amann, Ruth, Wyder, Stefan, Trueb, Beat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303837/
https://www.ncbi.nlm.nih.gov/pubmed/22432025
http://dx.doi.org/10.1371/journal.pone.0033457