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Structural Basis of Ets1 Cooperative Binding to Widely Separated Sites on Promoter DNA

Ets1 is a member of the Ets family of transcription factors. Ets1 is expressed in autoinhibited form and its DNA binding depends on partner proteins bound to adjacent sequences or the relative positioning of a second Ets-binding site (EBS). The autoinhibition of Ets1 is mediated by structural coupli...

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Detalles Bibliográficos
Autores principales: Babayeva, Nigar D., Baranovskaya, Oxana I., Tahirov, Tahir H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303851/
https://www.ncbi.nlm.nih.gov/pubmed/22432043
http://dx.doi.org/10.1371/journal.pone.0033698