Using Drosophila melanogaster as a Model for Genotoxic Chemical Mutational Studies with a New Program, SnpSift

This paper describes a new program SnpSift for filtering differential DNA sequence variants between two or more experimental genomes after genotoxic chemical exposure. Here, we illustrate how SnpSift can be used to identify candidate phenotype-relevant variants including single nucleotide polymorphi...

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Detalles Bibliográficos
Autores principales: Cingolani, Pablo, Patel, Viral M., Coon, Melissa, Nguyen, Tung, Land, Susan J., Ruden, Douglas M., Lu, Xiangyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304048/
https://www.ncbi.nlm.nih.gov/pubmed/22435069
http://dx.doi.org/10.3389/fgene.2012.00035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304048/
https://www.ncbi.nlm.nih.gov/pubmed/22435069
http://dx.doi.org/10.3389/fgene.2012.00035

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