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In vivo Large-Scale Cortical Mapping Using Channelrhodopsin-2 Stimulation in Transgenic Mice Reveals Asymmetric and Reciprocal Relationships between Cortical Areas

We have mapped intracortical activity in vivo independent of sensory input using arbitrary point channelrhodopsin-2 (ChR2) stimulation and regional voltage sensitive dye imaging in B6.Cg-Tg (Thy1-COP4/EYFP)18Gfng/J transgenic mice. Photostimulation of subsets of deep layer pyramidal neurons within f...

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Detalles Bibliográficos
Autores principales: Lim, Diana H., Mohajerani, Majid H., LeDue, Jeffrey, Boyd, Jamie, Chen, Shangbin, Murphy, Timothy H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304170/
https://www.ncbi.nlm.nih.gov/pubmed/22435052
http://dx.doi.org/10.3389/fncir.2012.00011