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Mutation of the histidin residue of the DRH motif in vasopressin V2 receptor expression and function

BACKGROUND AND THE PURPOSE OF THE STUDY: Vasopressin type 2 receptor (V2R), a G protein coupled receptor (GPCR), plays an important role in the regulation of renal antidiuretic function. The highly conserved DRH motif is essential for G protein signaling of V2R; however its role especially regarding...

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Detalles Bibliográficos
Autores principales: Mir Mohammad Sadeghi, H., Rabbani, M., Jafarian, A., Najafzadeh, H., Safaeian, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304347/
https://www.ncbi.nlm.nih.gov/pubmed/22615630