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Physico-mechanical and dissolution behaviours of ibuprofen crystals crystallized in the presence of various additives
BACKGROUND AND THE PURPOSE OF THE STUDY: The success of any direct-tableting procedure is strongly affected by the quality of the crystals used in the process. Ibuprofen is a poorly compactible drug with a high tendency for capping. In order to use ibuprofen in direct compression formulations, physi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tehran University of Medical Sciences
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304370/ https://www.ncbi.nlm.nih.gov/pubmed/22615598 |