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Physico-mechanical and dissolution behaviours of ibuprofen crystals crystallized in the presence of various additives

BACKGROUND AND THE PURPOSE OF THE STUDY: The success of any direct-tableting procedure is strongly affected by the quality of the crystals used in the process. Ibuprofen is a poorly compactible drug with a high tendency for capping. In order to use ibuprofen in direct compression formulations, physi...

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Detalles Bibliográficos
Autores principales: Nokhodchi, A., Amire, O., Jelvehgari, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304370/
https://www.ncbi.nlm.nih.gov/pubmed/22615598