Development and validation of a rapid HPLC- fluorescence method for simultaneous determination of venlafaxine and its major metabolites in human plasma

BACKGROUND AND THE PURPOSE OF THE STUDY: To develop a simple, rapid and accurate HPLC method for the measurement of the venlafaxine and its main metabolites, O-desmethylvenlafaxine and O,N-didesmethylvenlafaxine in pharmacokinetic studies and therapeutic drug monitoring. METHOD: Chromatographic sepa...

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Detalles Bibliográficos
Autores principales: Ardakani, Y. H., Foroumadi, A., Rouini, M.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304372/
https://www.ncbi.nlm.nih.gov/pubmed/22615601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304372/
https://www.ncbi.nlm.nih.gov/pubmed/22615601

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