Primary WWOX phosphorylation and JNK activation during etoposide induces cytotoxicity in HEK293 cells

BACKGROUND AND THE PURPOSE OF THE STUDY: Etoposide is an antineoplastic agent used in multiple cancers. It is known that etoposide induce cell death via interaction with topoisomerase II; however, the etopoisde cellular response is poorly understood. Upon etoposide induced DNA damage, many stress si...

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Detalles Bibliográficos
Autores principales: Jamshidiha, M., Habibollahi, P., Ostad, S.N., Ghahremani, M.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304374/
https://www.ncbi.nlm.nih.gov/pubmed/22615609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304374/
https://www.ncbi.nlm.nih.gov/pubmed/22615609

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