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Primary WWOX phosphorylation and JNK activation during etoposide induces cytotoxicity in HEK293 cells
BACKGROUND AND THE PURPOSE OF THE STUDY: Etoposide is an antineoplastic agent used in multiple cancers. It is known that etoposide induce cell death via interaction with topoisomerase II; however, the etopoisde cellular response is poorly understood. Upon etoposide induced DNA damage, many stress si...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Tehran University of Medical Sciences
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304374/ https://www.ncbi.nlm.nih.gov/pubmed/22615609 |