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Detection and characterisation of multi-drug resistance protein 1 (MRP-1) in human mitochondria
BACKGROUND: Overexpression of plasma membrane multi-drug resistance protein 1 (MRP-1) can lead to multidrug resistance. In this study, we describe for the first time the expression of mitochondrial MRP-1 in untreated human normal and cancer cells and tissues. METHODS: MRP-1 expression and subcellula...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304412/ https://www.ncbi.nlm.nih.gov/pubmed/22353810 http://dx.doi.org/10.1038/bjc.2012.40 |