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Microsatellite instability and Beta2-Microglobulin mutations as prognostic markers in colon cancer: results of the FOGT-4 trial

BACKGROUND: High-level microsatellite instability (MSI-H) has been reported as a prognostic marker in colon cancer. We here analysed the prognostic significance of MSI and mutations of the Beta2-Microglobulin (B2M) gene, which occur in about 30% of MSI-H colon cancer, in the cohort of the prospectiv...

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Detalles Bibliográficos
Autores principales: Tikidzhieva, A, Benner, A, Michel, S, Formentini, A, Link, K-H, Dippold, W, von Knebel Doeberitz, M, Kornmann, M, Kloor, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304421/
https://www.ncbi.nlm.nih.gov/pubmed/22353804
http://dx.doi.org/10.1038/bjc.2012.53