The Immunogenicity of the Tumor-Associated Antigen α-Fetoprotein Is Enhanced by a Fusion with a Transmembrane Domain

Aim. To investigate the ability of recombinant modified vaccinia virus Ankara (rMVA) vector to induce an immune response against a well-tolerated self-antigen. Methods. rMVA vectors expressing different form of α-fetoprotein (AFP) were produced and characterized. Naïve mice were vaccinated with MVA...

Descripción completa

Detalles Bibliográficos
Autores principales: Tran, Lucile, Judor, Jean-Paul, Gauttier, Vanessa, Geist, Michel, Hoffman, Chantal, Rooke, Ronald, Vassaux, Georges, Conchon, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304459/
https://www.ncbi.nlm.nih.gov/pubmed/22500109
http://dx.doi.org/10.1155/2012/878657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304459/
https://www.ncbi.nlm.nih.gov/pubmed/22500109
http://dx.doi.org/10.1155/2012/878657

Ejemplares similares