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The Immunogenicity of the Tumor-Associated Antigen α-Fetoprotein Is Enhanced by a Fusion with a Transmembrane Domain

Aim. To investigate the ability of recombinant modified vaccinia virus Ankara (rMVA) vector to induce an immune response against a well-tolerated self-antigen. Methods. rMVA vectors expressing different form of α-fetoprotein (AFP) were produced and characterized. Naïve mice were vaccinated with MVA...

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Detalles Bibliográficos
Autores principales:	Tran, Lucile, Judor, Jean-Paul, Gauttier, Vanessa, Geist, Michel, Hoffman, Chantal, Rooke, Ronald, Vassaux, Georges, Conchon, Sophie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304459/ https://www.ncbi.nlm.nih.gov/pubmed/22500109 http://dx.doi.org/10.1155/2012/878657

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