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Structure–function studies of a plant tyrosyl-DNA phosphodiesterase provide novel insights into DNA repair mechanisms of Arabidopsis thaliana

TDP1 (tyrosyl-DNA phosphodiesterase 1), a member of the PLD (phospholipase D) superfamily, catalyses the hydrolysis of a phosphodiester bond between a tyrosine residue and the 3′-phosphate of DNA. We have previously identified and characterized the AtTDP gene in Arabidopsis thaliana, an orthologue o...

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Detalles Bibliográficos
Autores principales: Kim, Hoyeun, Na, Sang Hyeon, Lee, So-Young, Jeong, Young-Min, Hwang, Hyun-Ju, Hur, Jae Young, Park, Sang-Hyun, Woo, Je-Chang, Kim, Sang-Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304491/
https://www.ncbi.nlm.nih.gov/pubmed/22214184
http://dx.doi.org/10.1042/BJ20111308