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Troglitazone Induces Extracellular Matrix and Cytoskeleton Remodeling in Mouse Collecting Duct Cells

Peroxisome proliferator-activated receptor (PPARγ) has been shown to have a protective role in the nephron through its ability to inhibit a transforming growth factor- (TGF-β) mediated fibrotic response. In contrast, PPARγ was also shown to induce a mesenchymal transformation in epithelial intestina...

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Detalles Bibliográficos
Autores principales: Corinaldi, Jaime, Nasrallah, Rania, Clark, Jordan, Paris, Geneviève, Miura, Pedro, Jasmin, Bernard J., Hébert, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304576/
https://www.ncbi.nlm.nih.gov/pubmed/22500093
http://dx.doi.org/10.1155/2012/507057