Analysis of Osteocalcin as a Candidate Gene for Type 2 Diabetes (T2D) and Intermediate Traits in Caucasians and African Americans

Recent studies in mice and human identified osteocalcin (OCN) as a bone-derived hormone that modulates insulin secretion and insulin sensitivity. OCN is synthesized by the bone gamma-carboxyglutamate protein (BGLAP) gene located in the well replicated region of type 2 diabetes (T2D) linkage on chrom...

Descripción completa

Detalles Bibliográficos
Autores principales: Das, Swapan K., Sharma, Neeraj K., Elbein, Steven C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2010
Materias:
Other
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304587/
https://www.ncbi.nlm.nih.gov/pubmed/20592451
http://dx.doi.org/10.3233/DMA-2010-0701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304587/
https://www.ncbi.nlm.nih.gov/pubmed/20592451
http://dx.doi.org/10.3233/DMA-2010-0701

Ejemplares similares