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Effects of IRF5 Lupus Risk Haplotype on Pathways Predicted to Influence B Cell Functions

Both genetic and environmental interactions affect systemic lupus erythematosus (SLE) development and pathogenesis. One known genetic factor associated with lupus is a haplotype of the interferon regulatory factor 5 (IRF5) gene. Analysis of global gene expression microarray data using gene set enric...

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Detalles Bibliográficos
Autores principales: Guthridge, Joel M., Clark, Daniel N., Templeton, Amanda, Dominguez, Nicolas, Lu, Rufei, Vidal, Gabriel S., Kelly, Jennifer A., Kauffman, Kenneth M., Harley, John B., Gaffney, Patrick M., James, Judith A., Poole, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304673/
https://www.ncbi.nlm.nih.gov/pubmed/22500098
http://dx.doi.org/10.1155/2012/594056