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Effects of IRF5 Lupus Risk Haplotype on Pathways Predicted to Influence B Cell Functions
Both genetic and environmental interactions affect systemic lupus erythematosus (SLE) development and pathogenesis. One known genetic factor associated with lupus is a haplotype of the interferon regulatory factor 5 (IRF5) gene. Analysis of global gene expression microarray data using gene set enric...
Autores principales: | Guthridge, Joel M., Clark, Daniel N., Templeton, Amanda, Dominguez, Nicolas, Lu, Rufei, Vidal, Gabriel S., Kelly, Jennifer A., Kauffman, Kenneth M., Harley, John B., Gaffney, Patrick M., James, Judith A., Poole, Brian D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304673/ https://www.ncbi.nlm.nih.gov/pubmed/22500098 http://dx.doi.org/10.1155/2012/594056 |
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