The 3′ Untranslated Regions of Influenza Genomic Sequences Are 5′PPP-Independent Ligands for RIG-I

Retinoic acid inducible gene-I (RIG-I) is a key regulator of antiviral immunity. RIG-I is generally thought to be activated by ssRNA species containing a 5′-triphosphate (PPP) group or by unphosphorylated dsRNA up to ∼300 bp in length. However, it is not yet clear how changes in the length, nucleoti...

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Detalles Bibliográficos
Autores principales: Davis, William G., Bowzard, J. Bradford, Sharma, Suresh D., Wiens, Mayim E., Ranjan, Priya, Gangappa, Shivaprakash, Stuchlik, Olga, Pohl, Jan, Donis, Ruben O., Katz, Jacqueline M., Cameron, Craig E., Fujita, Takashi, Sambhara, Suryaprakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305289/
https://www.ncbi.nlm.nih.gov/pubmed/22438882
http://dx.doi.org/10.1371/journal.pone.0032661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305289/
https://www.ncbi.nlm.nih.gov/pubmed/22438882
http://dx.doi.org/10.1371/journal.pone.0032661

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