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Integrated Sequence-Structure Motifs Suffice to Identify microRNA Precursors

BACKGROUND: Upwards of 1200 miRNA loci have hitherto been annotated in the human genome. The specific features defining a miRNA precursor and deciding its recognition and subsequent processing are not yet exhaustively described and miRNA loci can thus not be computationally identified with sufficien...

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Detalles Bibliográficos
Autores principales: Liu, Xiuqin, He, Shunmin, Skogerbø, Geir, Gong, Fuzhou, Chen, Runsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305290/
https://www.ncbi.nlm.nih.gov/pubmed/22438883
http://dx.doi.org/10.1371/journal.pone.0032797