Age-Related Memory Impairment Is Associated with Disrupted Multivariate Epigenetic Coordination in the Hippocampus

Mounting evidence linking epigenetic regulation to memory-related synaptic plasticity raises the possibility that altered chromatin modification dynamics might contribute to age-dependent cognitive decline. Here we show that the coordinated orchestration of both baseline and experience-dependent epi...

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Detalles Bibliográficos
Autores principales: Castellano, James F., Fletcher, Bonnie R., Kelley-Bell, Bennett, Kim, David H., Gallagher, Michela, Rapp, Peter R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305324/
https://www.ncbi.nlm.nih.gov/pubmed/22438904
http://dx.doi.org/10.1371/journal.pone.0033249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305324/
https://www.ncbi.nlm.nih.gov/pubmed/22438904
http://dx.doi.org/10.1371/journal.pone.0033249

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