Cargando…

Age-Related Memory Impairment Is Associated with Disrupted Multivariate Epigenetic Coordination in the Hippocampus

Mounting evidence linking epigenetic regulation to memory-related synaptic plasticity raises the possibility that altered chromatin modification dynamics might contribute to age-dependent cognitive decline. Here we show that the coordinated orchestration of both baseline and experience-dependent epi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Castellano, James F., Fletcher, Bonnie R., Kelley-Bell, Bennett, Kim, David H., Gallagher, Michela, Rapp, Peter R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305324/ https://www.ncbi.nlm.nih.gov/pubmed/22438904 http://dx.doi.org/10.1371/journal.pone.0033249

Ejemplares similares

Genetic disruption of the core circadian clock impairs hippocampus-dependent memory
por: Wardlaw, Sarah M., et al.
Publicado: (2014)

Differential Retinoic Acid Signaling in the Hippocampus of Aged Rats with and without Memory Impairment
por: Wołoszynowska-Fraser, Marta U., et al.
Publicado: (2021)

Acute Disruption of the Dorsal Hippocampus Impairs the Encoding and Retrieval of Trace Fear Memories
por: Wilmot, Jacob H., et al.
Publicado: (2019)

Postnatal dysregulation of Notch signal disrupts dendrite development of adult-born neurons in the hippocampus and contributes to memory impairment
por: Ding, Xue-Feng, et al.
Publicado: (2016)

Endogenous retroviruses are associated with hippocampus-based memory impairment
por: Sankowski, Roman, et al.
Publicado: (2019)

Norepinephrine, beyond the Synapse: Coordinating Epigenetic Codes for Memory
por: Maity, Sabyasachi, et al.
Publicado: (2022)

Hippocampal Deletion of CB1 Receptor Impairs Social Memory and Leads to Age-Related Changes in the Hippocampus of Adult Mice
por: Palmisano, Michela, et al.
Publicado: (2022)

Cortical reactivation of spatial and non-spatial features coordinates with hippocampus to form a memory dialogue
por: Chang, HaoRan, et al.
Publicado: (2023)

Coordinated representational reinstatement in the human hippocampus and lateral temporal cortex during episodic memory retrieval
por: Pacheco Estefan, D., et al.
Publicado: (2019)

Different theta frameworks coexist in the rat hippocampus and are coordinated during memory-guided and novelty tasks
por: López-Madrona, Víctor J, et al.
Publicado: (2020)

Ablation of BRaf Impairs Neuronal Differentiation in the Postnatal Hippocampus and Cerebellum
por: Pfeiffer, Verena, et al.
Publicado: (2013)

Smad7 in the hippocampus contributes to memory impairment in aged mice after anesthesia and surgery
por: Liu, Changliang, et al.
Publicado: (2023)

β-amyloid disrupts human NREM slow waves and related hippocampus-dependent memory consolidation
por: Mander, Bryce A., et al.
Publicado: (2015)

Age-associated gut microbiota impair hippocampus-dependent memory in a vagus-dependent manner
por: Rei, Damien, et al.
Publicado: (2022)

Western diet consumption impairs memory function via dysregulated hippocampus acetylcholine signaling
por: Hayes, Anna M. R., et al.
Publicado: (2023)

Prefrontal atrophy, disrupted NREM slow waves, and impaired hippocampal-dependent memory in aging
por: Mander, Bryce A., et al.
Publicado: (2013)

Neurochemical changes in the hippocampus and prefrontal cortex associated with electroacupuncture for learning and memory impairment
por: He, Jian, et al.
Publicado: (2018)

Aging Disrupts the Circadian Patterns of Protein Expression in the Murine Hippocampus
por: Adler, Paula, et al.
Publicado: (2020)

High Caloric Diet Induces Memory Impairment and Disrupts Synaptic Plasticity in Aged Rats
por: Paulo, Sara L., et al.
Publicado: (2021)

Theta Coordinated Error-Driven Learning in the Hippocampus
por: Ketz, Nicholas, et al.
Publicado: (2013)

Rapid coordination of effective learning by the human hippocampus
por: Kragel, James E., et al.
Publicado: (2021)

Rhythmic Memory Consolidation in the Hippocampus
por: Nokia, Miriam S., et al.
Publicado: (2022)

Select Overexpression of Homer1a in Dorsal Hippocampus Impairs Spatial Working Memory
por: Celikel, Tansu, et al.
Publicado: (2007)

Complement-associated loss of CA2 inhibitory synapses in the demyelinated hippocampus impairs memory
por: Ramaglia, Valeria, et al.
Publicado: (2021)

Decreased Npas4 and Arc mRNA Levels in the Hippocampus of Aged Memory‐Impaired Wild‐Type But Not Memory Preserved 11β‐HSD1 Deficient Mice
por: Qiu, J., et al.
Publicado: (2016)

Cerebellar disruption impairs working memory during evidence accumulation
por: Deverett, Ben, et al.
Publicado: (2019)

Epigenetic gene expression links heart failure to memory impairment
por: Islam, Md Rezaul, et al.
Publicado: (2021)

Resistance exercise improves hippocampus-dependent memory
por: Cassilhas, R.C., et al.
Publicado: (2012)

Growth disrupting mutations in epigenetic regulatory molecules are associated with abnormalities of epigenetic aging
por: Jeffries, Aaron R., et al.
Publicado: (2019)

Preferential loss of dorsal-hippocampus synapses underlies memory impairments provoked by short, multimodal stress
por: Maras, P M, et al.
Publicado: (2014)

Loss of molars early in life develops behavioral lateralization and impairs hippocampus-dependent recognition memory
por: Kawahata, Masatsuna, et al.
Publicado: (2014)

The effects of doxepin on stress-induced learning, memory impairments, and TNF-α level in the rat hippocampus
por: Azadbakht, Ali Ahmad, et al.
Publicado: (2015)

Osmotin attenuates amyloid beta-induced memory impairment, tau phosphorylation and neurodegeneration in the mouse hippocampus
por: Ali, Tahir, et al.
Publicado: (2015)

Repetitive Pain in Neonatal Male Rats Impairs Hippocampus-Dependent Fear Memory Later in Life
por: Xia, Dongqing, et al.
Publicado: (2020)

Mild Behavioral Impairment Is Associated With Atrophy of Entorhinal Cortex and Hippocampus in a Memory Clinic Cohort
por: Matuskova, Veronika, et al.
Publicado: (2021)

Methamphetamine Exposure in Adolescent Impairs Memory of Mice in Adulthood Accompanied by Changes in Neuroplasticity in the Dorsal Hippocampus
por: Liang, Min, et al.
Publicado: (2022)

Relational Memory and the Hippocampus: Representations and Methods
por: Konkel, Alex, et al.
Publicado: (2009)

An event map of memory space in the hippocampus
por: Deuker, Lorena, et al.
Publicado: (2016)

The hippocampus as the switchboard between perception and memory
por: Treder, Matthias S., et al.
Publicado: (2021)

Auras localized to the temporal lobe disrupt verbal memory and learning — Causal evidence from direct electrical stimulation of the hippocampus
por: Pizarro, Diana, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_q6i8k6sduq8g3jpvf4is2f057f