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Nicotinic Acetylcholine Receptor Variants Are Related to Smoking Habits, but Not Directly to COPD

Genome-wide association studies identified single nucleotide polymorphisms (SNPs) in the nicotinic acetylcholine receptors (nAChRs) cluster as a risk factor for nicotine dependency and COPD. We investigated whether SNPs in the nAChR cluster are associated with smoking habits and lung function declin...

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Detalles Bibliográficos
Autores principales: Budulac, Simona E., Vonk, Judith M., Postma, Dirkje S., Siedlinski, Mateusz, Timens, Wim, Boezen, Marike H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305325/
https://www.ncbi.nlm.nih.gov/pubmed/22438921
http://dx.doi.org/10.1371/journal.pone.0033386