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Llama Antibody Fragments Recognizing Various Epitopes of the CD4bs Neutralize a Broad Range of HIV-1 Subtypes A, B and C

Many of the neutralising antibodies, isolated to date, display limited activities against the globally most prevalent HIV-1 subtypes A and C. Therefore, those subtypes are considered to be an important target for antibody-based therapy. Variable domains of llama heavy chain antibodies (VHH) have som...

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Detalles Bibliográficos
Autores principales: Strokappe, Nika, Szynol, Agnieszka, Aasa-Chapman, Marlèn, Gorlani, Andrea, Forsman Quigley, Anna, Hulsik, David Lutje, Chen, Lei, Weiss, Robin, de Haard, Hans, Verrips, Theo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305327/
https://www.ncbi.nlm.nih.gov/pubmed/22438910
http://dx.doi.org/10.1371/journal.pone.0033298