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Network Evolution: Rewiring and Signatures of Conservation in Signaling
The analysis of network evolution has been hampered by limited availability of protein interaction data for different organisms. In this study, we investigate evolutionary mechanisms in Src Homology 3 (SH3) domain and kinase interaction networks using high-resolution specificity profiles. We constru...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305342/ https://www.ncbi.nlm.nih.gov/pubmed/22438796 http://dx.doi.org/10.1371/journal.pcbi.1002411 |