An Alu Element–Associated Hypermethylation Variant of the POMC Gene Is Associated with Childhood Obesity

The individual risk for common diseases not only depends on genetic but also on epigenetic polymorphisms. To assess the role of epigenetic variations in the individual risk for obesity, we have determined the methylation status of two CpG islands at the POMC locus in obese and normal-weight children...

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Detalles Bibliográficos
Autores principales: Kuehnen, Peter, Mischke, Mona, Wiegand, Susanna, Sers, Christine, Horsthemke, Bernhard, Lau, Susanne, Keil, Thomas, Lee, Young-Ae, Grueters, Annette, Krude, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305357/
https://www.ncbi.nlm.nih.gov/pubmed/22438814
http://dx.doi.org/10.1371/journal.pgen.1002543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305357/
https://www.ncbi.nlm.nih.gov/pubmed/22438814
http://dx.doi.org/10.1371/journal.pgen.1002543

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