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An Alu Element–Associated Hypermethylation Variant of the POMC Gene Is Associated with Childhood Obesity
The individual risk for common diseases not only depends on genetic but also on epigenetic polymorphisms. To assess the role of epigenetic variations in the individual risk for obesity, we have determined the methylation status of two CpG islands at the POMC locus in obese and normal-weight children...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305357/ https://www.ncbi.nlm.nih.gov/pubmed/22438814 http://dx.doi.org/10.1371/journal.pgen.1002543 |