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Antagonistic Regulation of Apoptosis and Differentiation by the Cut Transcription Factor Represents a Tumor-Suppressing Mechanism in Drosophila

Apoptosis is essential to prevent oncogenic transformation by triggering self-destruction of harmful cells, including those unable to differentiate. However, the mechanisms linking impaired cell differentiation and apoptosis during development and disease are not well understood. Here we report that...

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Detalles Bibliográficos
Autores principales: Zhai, Zongzhao, Ha, Nati, Papagiannouli, Fani, Hamacher-Brady, Anne, Brady, Nathan, Sorge, Sebastian, Bezdan, Daniela, Lohmann, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305397/
https://www.ncbi.nlm.nih.gov/pubmed/22438831
http://dx.doi.org/10.1371/journal.pgen.1002582