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Antagonistic Regulation of Apoptosis and Differentiation by the Cut Transcription Factor Represents a Tumor-Suppressing Mechanism in Drosophila
Apoptosis is essential to prevent oncogenic transformation by triggering self-destruction of harmful cells, including those unable to differentiate. However, the mechanisms linking impaired cell differentiation and apoptosis during development and disease are not well understood. Here we report that...
Autores principales: | Zhai, Zongzhao, Ha, Nati, Papagiannouli, Fani, Hamacher-Brady, Anne, Brady, Nathan, Sorge, Sebastian, Bezdan, Daniela, Lohmann, Ingrid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305397/ https://www.ncbi.nlm.nih.gov/pubmed/22438831 http://dx.doi.org/10.1371/journal.pgen.1002582 |
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