Exacerbation of experimental autoimmune encephalomyelitis in prion protein (PrPc)-null mice: evidence for a critical role of the central nervous system

BACKGROUND: The cellular prion protein (PrPc) is a host-encoded glycoprotein whose transconformation into PrP scrapie (PrPSc) initiates prion diseases. The role of PrPc in health is still obscure, but many candidate functions have been attributed to the protein, both in the immune and the nervous sy...

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Detalles Bibliográficos
Autores principales: Gourdain, Pauline, Ballerini, Clara, Nicot, Arnaud B, Carnaud, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305405/
https://www.ncbi.nlm.nih.gov/pubmed/22281016
http://dx.doi.org/10.1186/1742-2094-9-25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305405/
https://www.ncbi.nlm.nih.gov/pubmed/22281016
http://dx.doi.org/10.1186/1742-2094-9-25

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