Neurobeachin, a Regulator of Synaptic Protein Targeting, Is Associated with Body Fat Mass and Feeding Behavior in Mice and Body-Mass Index in Humans

Neurobeachin (Nbea) regulates neuronal membrane protein trafficking and is required for the development and functioning of central and neuromuscular synapses. In homozygous knockout (KO) mice, Nbea deficiency causes perinatal death. Here, we report that heterozygous KO mice haploinsufficient for Nbe...

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Detalles Bibliográficos
Autores principales: Olszewski, Pawel K., Rozman, Jan, Jacobsson, Josefin A., Rathkolb, Birgit, Strömberg, Siv, Hans, Wolfgang, Klockars, Anica, Alsiö, Johan, Risérus, Ulf, Becker, Lore, Hölter, Sabine M., Elvert, Ralf, Ehrhardt, Nicole, Gailus-Durner, Valérie, Fuchs, Helmut, Fredriksson, Robert, Wolf, Eckhard, Klopstock, Thomas, Wurst, Wolfgang, Levine, Allen S., Marcus, Claude, Hrabě de Angelis, Martin, Klingenspor, Martin, Schiöth, Helgi B., Kilimann, Manfred W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305408/
https://www.ncbi.nlm.nih.gov/pubmed/22438821
http://dx.doi.org/10.1371/journal.pgen.1002568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305408/
https://www.ncbi.nlm.nih.gov/pubmed/22438821
http://dx.doi.org/10.1371/journal.pgen.1002568

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