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Spt6 levels are modulated by PAAF1 and proteasome to regulate the HIV-1 LTR
BACKGROUND: Tat-mediated activation of the HIV-1 promoter depends upon a proteasome-associated factor, PAAF1, which dissociates 26S proteasome to produce 19S RP that is essential for transcriptional elongation. The effect of PAAF1 on proteasome activity could also potentially shield certain factors...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305501/ https://www.ncbi.nlm.nih.gov/pubmed/22316138 http://dx.doi.org/10.1186/1742-4690-9-13 |