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Expression and localization of claudins-3 and -12 in transformed human brain endothelium

BACKGROUND: The aim of this study was to characterize the hCMEC/D3 cell line, an in vitro model of the human Blood Brain Barrier (BBB) for the expression of brain endothelial specific claudins-3 and -12. FINDINGS: hCMEC/D3 cells express claudins-3 and -12. Claudin-3 is distinctly localized to the TJ...

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Detalles Bibliográficos
Autores principales: Schrade, Anja, Sade, Hadassah, Couraud, Pierre-Olivier, Romero, Ignacio A, Weksler, Babette B, Niewoehner, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305566/
https://www.ncbi.nlm.nih.gov/pubmed/22373538
http://dx.doi.org/10.1186/2045-8118-9-6