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High serum alkaline phosphatase cooperating with MMP-9 predicts metastasis and poor prognosis in patients with primary osteosarcoma in Southern China

BACKGROUND: Osteosarcoma is a malignant tumor with high ability to form invasion and metastasis. Identifying prognostic factor in osteosarcoma is helpful to select those patients for more aggressive management. Our study evaluated serum alkaline phosphatase (ALP) cooperating with matrix metalloprote...

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Detalles Bibliográficos
Autores principales: Han, Ju, Yong, Bicheng, Luo, Canqiao, Tan, Pingxian, Peng, Tingsheng, Shen, Jingnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305572/
https://www.ncbi.nlm.nih.gov/pubmed/22333159
http://dx.doi.org/10.1186/1477-7819-10-37