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A Coupled Discrete/Continuum Model for Describing Cancer-Therapeutic Transport in the Lung

We propose a computational simulation framework for describing cancer-therapeutic transport in the lung. A discrete vascular graph model (VGM) is coupled to a double-continuum model (DCM) to determine the amount of administered therapeutic agent that will reach the cancer cells. An alveolar cell car...

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Detalles Bibliográficos
Autores principales: Erbertseder, Karin, Reichold, Johannes, Flemisch, Bernd, Jenny, Patrick, Helmig, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305605/
https://www.ncbi.nlm.nih.gov/pubmed/22438873
http://dx.doi.org/10.1371/journal.pone.0031966