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Hsp90 is important for fecundity, longevity, and buffering of cryptic deleterious variation in wild fly populations

BACKGROUND: In the laboratory, the Drosophila melanogaster heat shock protein Hsp90 can buffer the phenotypic effects of genetic variation. Laboratory experiments either manipulate Hsp90 activity pharmacologically, or they induce mutations with strong effects in the gene Hsp83, the single-copy fly g...

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Detalles Bibliográficos
Autores principales: Chen, Bing, Wagner, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305614/
https://www.ncbi.nlm.nih.gov/pubmed/22369091
http://dx.doi.org/10.1186/1471-2148-12-25