Following Ariadne's thread: a new perspective on RBR ubiquitin ligases

Ubiquitin signaling pathways rely on E3 ligases for effecting the final transfer of ubiquitin from E2 ubiquitin conjugating enzymes to a protein target. Here we re-evaluate the hybrid RING/HECT mechanism used by the E3 family RING-between-RINGs (RBRs) to transfer ubiquitin to substrates. We place RB...

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Detalles Bibliográficos
Autores principales: Wenzel, Dawn M, Klevit, Rachel E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305615/
https://www.ncbi.nlm.nih.gov/pubmed/22420831
http://dx.doi.org/10.1186/1741-7007-10-24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305615/
https://www.ncbi.nlm.nih.gov/pubmed/22420831
http://dx.doi.org/10.1186/1741-7007-10-24

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