Reference genome-independent assessment of mutation density using restriction enzyme-phased sequencing

BACKGROUND: The availability of low cost sequencing has spurred its application to discovery and typing of variation, including variation induced by mutagenesis. Mutation discovery is challenging as it requires a substantial amount of sequencing and analysis to detect very rare changes and distingui...

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Detalles Bibliográficos
Autores principales: Monson-Miller, Jennifer, Sanchez-Mendez, Diana C, Fass, Joseph, Henry, Isabelle M, Tai, Thomas H, Comai, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305632/
https://www.ncbi.nlm.nih.gov/pubmed/22333298
http://dx.doi.org/10.1186/1471-2164-13-72

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305632/
https://www.ncbi.nlm.nih.gov/pubmed/22333298
http://dx.doi.org/10.1186/1471-2164-13-72

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