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Reference genome-independent assessment of mutation density using restriction enzyme-phased sequencing
BACKGROUND: The availability of low cost sequencing has spurred its application to discovery and typing of variation, including variation induced by mutagenesis. Mutation discovery is challenging as it requires a substantial amount of sequencing and analysis to detect very rare changes and distingui...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305632/ https://www.ncbi.nlm.nih.gov/pubmed/22333298 http://dx.doi.org/10.1186/1471-2164-13-72 |