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Galectin-8 in IgA Nephritis: Decreased Binding of IgA by Galectin-8 Affinity Chromatography and Associated Increased Binding in Non-IgA Serum Glycoproteins

BACKGROUND: Immunoglobulin A nephritis (IgAN) is the most common primary glomerulonephritis worldwide. It is caused by accumulation of IgA1-containing immune complexes in the kidney resulting in renal failure, which is thought to be due to altered glycosylation of IgA with a decrease of 2–3-sialylat...

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Detalles Bibliográficos
Autores principales: Carlsson, Michael C., Bakoush, Omran, Tengroth, Lotta, Kilsgård, Ola, Malmström, Johan, Hellmark, Thomas, Segelmark, Mårten, Leffler, Hakon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305883/
https://www.ncbi.nlm.nih.gov/pubmed/22173878
http://dx.doi.org/10.1007/s10875-011-9618-3