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Carbonic anhydrase IX is a predictive marker of doxorubicin resistance in early-stage breast cancer independent of HER2 and TOP2A amplification

BACKGROUND: In early-stage breast cancer, adjuvant chemotherapy is associated with significant systemic toxicity with only a modest survival benefit. Therefore, there is considerable interest in identifying predictive markers of response to therapy. Doxorubicin, one of the most common drugs used to...

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Detalles Bibliográficos
Autores principales: Betof, A S, Rabbani, Z N, Hardee, M E, Kim, S J, Broadwater, G, Bentley, R C, Snyder, S A, Vujaskovic, Z, Oosterwijk, E, Harris, L N, Horton, J K, Dewhirst, M W, Blackwell, K L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305967/
https://www.ncbi.nlm.nih.gov/pubmed/22333602
http://dx.doi.org/10.1038/bjc.2012.32