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Circulating sphingosine-1-phosphate and erythrocyte sphingosine kinase-1 activity as novel biomarkers for early prostate cancer detection

BACKGROUND: Current markers available for screening normal populations and for monitoring prostate cancer (PCa) treatment lack sensitivity and selectivity. Sphingosine-1-phosphate (S1P) is a circulating lipid second messenger involved in cell growth and migration, the immune response, angiogenesis,...

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Detalles Bibliográficos
Autores principales: Nunes, J, Naymark, M, Sauer, L, Muhammad, A, Keun, H, Sturge, J, Stebbing, J, Waxman, J, Pchejetski, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305969/
https://www.ncbi.nlm.nih.gov/pubmed/22315056
http://dx.doi.org/10.1038/bjc.2012.14