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Silver triflate catalyzed synthesis of 3-aminoalkylated indoles and evaluation of their antibacterial activities
An efficient, one-pot synthesis was developed for 3-aminoalkylated indoles by three-component coupling reaction of aldehydes, N-methylanilines, and indoles using AgOTf as a catalyst. A series of twenty 3-aminoalkylated indoles was evaluated for their antibacterial activities against both Gram negati...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306001/ https://www.ncbi.nlm.nih.gov/pubmed/22373086 http://dx.doi.org/10.1186/2191-2858-1-10 |