Detection of oligoclonal IgG kappa and IgG lambda bands in cerebrospinal fluid and serum with Hevylite™ antibodies. comparison with the free light chain oligoclonal pattern

BACKGROUND: Oligoclonal IgG bands in cerebrospinal fluid that are absent in serum indicate intrathecal IgG synthesis and are a sensitive marker of CNS inflammatory diseases, in particular multiple sclerosis. It may be of interest to determine whether these bands are predominantly IgGκ or IgGλ. METHO...

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Detalles Bibliográficos
Autores principales: Zeman, David, Hradílek, Pavel, Švagera, Zdeněk, Mojžíšková, Eva, Woznicová, Ivana, Zapletalová, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306208/
https://www.ncbi.nlm.nih.gov/pubmed/22360869
http://dx.doi.org/10.1186/2045-8118-9-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306208/
https://www.ncbi.nlm.nih.gov/pubmed/22360869
http://dx.doi.org/10.1186/2045-8118-9-5

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