Development of Myelodysplastic Syndrome and Acute Myeloid Leukemia 15 Years after Hydroxyurea Use in a Patient with Sickle Cell Anemia

We report a 41 year old male with sickle cell disease who developed a myelodysplastic syndrome and acute myeloid leukemia with complex karyotype involving chromosomes 5, 7 and 17 after 15 years of hydroxyurea treatment. He responded poorly to induction chemotherapy with cytarabine/idarubicin followe...

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Detalles Bibliográficos
Autores principales: Baz, Walid, Najfeld, Vesna, Yotsuya, Matthew, Talwar, Jotica, Terjanian, Terenig, Forte, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306229/
https://www.ncbi.nlm.nih.gov/pubmed/22550403
http://dx.doi.org/10.4137/CMO.S8810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306229/
https://www.ncbi.nlm.nih.gov/pubmed/22550403
http://dx.doi.org/10.4137/CMO.S8810

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