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Escherichia coli Frameshift Mutation Rate Depends on the Chromosomal Context but Not on the GATC Content Near the Mutation Site

Different studies have suggested that mutation rate varies at different positions in the genome. In this work we analyzed if the chromosomal context and/or the presence of GATC sites can affect the frameshift mutation rate in the Escherichia coli genome. We show that in a mismatch repair deficient b...

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Detalles Bibliográficos
Autores principales: Martina, Mariana A., Correa, Elisa M. E., Argaraña, Carlos E., Barra, José L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306285/
https://www.ncbi.nlm.nih.gov/pubmed/22438985
http://dx.doi.org/10.1371/journal.pone.0033701