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Inhibition of ERβ Induces Resistance to Cisplatin by Enhancing Rad51–Mediated DNA Repair in Human Medulloblastoma Cell Lines

Cisplatin is one of the most widely used and effective anticancer drugs against solid tumors including cerebellar tumor of the childhood, Medulloblastoma. However, cancer cells often develop resistance to cisplatin, which limits therapeutic effectiveness of this otherwise effective genotoxic drug. I...

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Detalles Bibliográficos
Autores principales: Wilk, Anna, Waligorska, Agnieszka, Waligorski, Piotr, Ochoa, Augusto, Reiss, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306313/
https://www.ncbi.nlm.nih.gov/pubmed/22439007
http://dx.doi.org/10.1371/journal.pone.0033867